Publicación:
New fluorescent turn-off probes for highly aensitive and selective detection of SO2derivatives in a micellar media

Vista sencilla de ítem
dc.contributor.authorGómez, Marisol
dc.contributor.authorPérez, Edwin G.
dc.contributor.authorArancibia, Verónica
dc.contributor.authorIribarren, Constanza
dc.contributor.authorBravo-Díaz, Carlos
dc.contributor.authorGarcía-Beltrán, Olimpo
dc.contributor.authorAliaga, Margarita E.
dc.date.accessioned2019-03-04T16:39:54Z
dc.date.available2019-03-04T16:39:54Z
dc.date.issued2017-01-20
dc.description.abstractIn this work, two isoxazole derivatives (1 and 2) were synthesized and characterized using common spectroscopic tools. The chemosensor behavior of 1 and 2 toward various analytes was explored and we found that both probes follow a ‘switch-off’ mechanism during SO2-derivatives sensing, with limits of detection near 10−6 and 10−5 M, respectively. A recognition mechanism is proposed, based on a Michael-type addition reaction toward the probes, induced by SO2-derivatives and favored by micellar media. Typical interferences like glutathione (GSH) and cysteine (Cys) were inhibited by the presence of the cationic micelles of cetylpyridinium bromide (CPB) and the zwitterionic micelle of sulfobetaine (SB3-14); the detection limits were considerably improved. Thus, on the basis of these results, it is suggested that the use of these kinds of surfactants can be considered as a strategy for optimizing the detection of sulfite via its addition reaction to activated olefins containing isoxazole. Finally, probe 1 was chosen as the best sensor since it was assessed to detect SO2-derivatives in real samples (red and white wines) and in a biological system (Caco-2 cells) with very good results.es_CO
dc.identifier.citationGómez, M., Perez, E. G., Arancibia, V., Iribarren, C., Bravo-Díaz, C., García-Beltrán, O., & Aliaga, M. E. (2017). New fluorescent turn-off probes for highly sensitive and selective detection of SO2 derivatives in a micellar media. Sensors and Actuators B: Chemical, 238, 578–587.es_CO
dc.identifier.issn0925-4005
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0925400516311510
dc.language.isoenes_CO
dc.publisherSensors and Actuators B: Chemicales_CO
dc.subjectIsoxazole derivativeses_CO
dc.subjectBisulfite detectiones_CO
dc.subjectTurn off fluorescencees_CO
dc.subjectMicellar mediaes_CO
dc.subjectMichael-type additiones_CO
dc.titleNew fluorescent turn-off probes for highly aensitive and selective detection of SO2derivatives in a micellar mediaes_CO
dc.typeArticlees_CO
dspace.entity.typePublication
eperson.emailjose.garcia@unibague.edu.coes_CO
Archivos
Bloque de licencias
Mostrando1 - 1 de 1
Miniatura
Nombre:
license.txt
Tamaño:
134 B
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Artículos