Examinando por Autor "Fuentes-Estrada, Marcial"
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- PublicaciónSólo datosA selective thioxothiazolidin-coumarin probe for Hg2+ based on its desulfurization reaction. Exploring its potential for live cell imaging(Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2020-01-01) Aliaga, Margarita E.; Gazitua, Marcela; Rojas-Bolaños, Andrea; Fuentes-Estrada, Marcial; Durango, Diego; García-Beltrán, OlimpoSensing the most toxic heavy metal (mercury) has attracted a lot of attention in recent years due to its extreme harmfulness to both human health and the environment. Thus, we reported herein the synthesis, spectroscopic and kinetic characterization, and biological evaluation of a new thioxothiazolidin coumarin derivative (ILA92), which undergoes a desulfurization reaction induced by mercuric ions (Hg2+). This process is the origin of a selective sensing of Hg2+ ions in aqueous solution by colorimetric and fluorescent methods. Furthermore, the probe showed great potential for imaging Hg2+ in living cells.
- PublicaciónSólo datosDevelopment of a Low-Cost UV-Vis Spectrophotometer and Its Application for the Detection of Mercuric Ions Assisted by Chemosensors(Sensors, 2020-02-08) González-Morales, David; Valencia, Asmilly; Díaz-Núñez, Astrid; Fuentes-Estrada, Marcial; López-Santos, Oswaldo; García-Beltrán, OlimpoDetection of an environmental contaminant requires the use of expensive measurement equipment, which limits the realization of in situ tests because of their high cost, their limited portability, or the extended time duration of the tests. This paper presents in detail the development of a portable low-cost spectrophotometer which, by using a specialized chemosensor, allows detection of mercuric ions (Hg2+), providing effective and accurate results. Design specifications for all the stages assembling the spectrophotometer and the elements selected to build them are presented along with the process to synthesize the chemosensor and the tests developed to validate its performance in comparison with a high-precision commercial laboratory spectrophotometer.
- PublicaciónSólo datosErythrinoid and indol alkaloids isolated from the seeds of Erythrina rubrinervia Kunth: Chemotaxonomic significance(Biochemical Systematics and Ecology, 2021-06-16) Urrea Florián, Simón; Sepúlveda, Beatriz; Torres-Benítez, Alfredo; Simirgiotis, Mario J.; Fuentes-Estrada, Marcial; Areche, Carlos; García Beltrán, OlimpoIn the present work, we report the isolation of five alkaloids from the seeds of Erythrina rubrinervia. Four of the isolated alkaloids are erythrinoid type alkaloids which were identified as erysodine (1), erysovine (2), erythraline (3) and erysotrine (4), plus an indolic alkaloid which was identified as hypaphorine (5). The analysis of spectroscopic data for the alkaloid l-hypaphorine shows that the published structure (5a) must be revised, and the correct structure is that depicted as the structure 5c. The chemical structures were elucidated by full spectroscopic analysis. The chemotaxonomic significance of those findings in the genus Erythrina is also discussed.
- PublicaciónAcceso abiertoGC/MS profile and antifungal activity of Zanthoxylum caribaeum lam essential oil against Moniliophthora roreri cif and par, a pathogen that infects Theobroma cacao l crops in the tropics(2023-08-10) Fuentes-Estrada, Marcial; Duarte, Diannefair; Areche, Carlos; Stashenko, Elena; Pino Benítez, Nayive; Bárcenas-Pérez, Daniela; Cheel, José; García-Beltrán, Olimpo; Saavedra-Barrera Rogerio; Jiménez-González AndreaThe species Zanthoxylum caribaeum belongs to the Rutaceae family, from which several chemical nuclei are known, including alkaloids and coumarins. In addition, its essential oil has been characterized, showing differences in composition and various antimicrobial activities. In the present study, the essential oil of Z. caribaeum collected in the department of Tolima, central Colombia, was characterized by gas chromatography with mass selective detector (GC-MS). The essential oil showed a composition of about 43 compounds (including major and minor), whose main components, according to their abundance, are the following: germacrene D (228.0 1.6 mg/g EO), (E)–farnesene (128.0 1.5 mg/g EO), -elemene (116.0 1.6 mg/g EO) and (E)-nerolidol (74.0 2.2 mg/g EO). This oil was tested against microorganisms that affect cocoa production in Colombia and in tropical countries where the production of this commodity is very important for the economy. The antifungal tests were performed on the fungal species Moniliophthora roreri and showed promising and significant activity, inhibiting growth by more than 95% at concentrations of 50 L/mL and 100 L/mL. This remarkable antifungal activity could be due to the presence of major and minor compounds that synergistically enhance the activity.